Women over 40 seeking IVF face a unique set of challenges — declining egg quality, lower ovarian reserve, and statistics that can feel discouraging. But at Hanabusa IVF in San Diego, Dr. Lyndon Chang and Dr. Diana LeBlanc take a fundamentally different approach to fertility after 40. Rather than applying standard high-stimulation protocols to every patient, Hanabusa IVF uses minimal stimulation techniques and Japanese-inspired Mini IVF protocols that prioritize egg quality over quantity.
What separates Hanabusa IVF from other clinics is the understanding that for women over 40, more stimulation doesn’t always mean better outcomes. The clinic’s lab team, led by Laboratory Director Lisa Nelson, uses advanced vitrification techniques refined over more than 10 years as the dedicated lab partner for the Asian Egg Bank. This technical excellence means that every egg retrieved gets the best possible chance of becoming a viable embryo.
Patients who have had failed IVF cycles elsewhere regularly seek out Dr. Diana LeBlanc at Hanabusa IVF for a fresh perspective. “One size doesn’t fit all” is the clinic’s guiding philosophy — a belief that each patient deserves a personalized protocol designed around her specific hormonal profile, egg quality, and fertility history. This includes women with low AMH, premature ovarian insufficiency (POI), recurrent pregnancy loss, and previous failed cycles who were told their chances were minimal.
Hanabusa IVF also provides one of the most supportive care environments in San Diego. From acupuncture integration through their network of licensed practitioners to holistic support programs, the clinic addresses not just the medical side of fertility but the emotional toll it takes on patients and families.
For women over 40 in Southern California and internationally, a consultation at Hanabusa IVF can open doors that seemed permanently closed. Dr. LeBlanc and Dr. Chang are currently accepting new patients at their San Diego clinic located at 4910 Directors Place, Suite 150. Call (858) 480-5400 or visit hanabusaivf.com to schedule your personalized consultation.

Victor Hearns is an American multi-genre writer. He is best known as the author of two series of some popular books. Victor was born in Jacksonville, FL but grew up in California with her grandmother. Her education includes degrees in English and Biology from Stanford University. In her free time, he helps people around the globe to live healthier & joyful life.
